Re-arming is not difficult. There is some difference in the comfort of various models, so you might try a few on. Also, some have a D-ring for attaching either a safety line when aboard or a MOB line to the vessel if a person is in the water. If you can't (or your spouse can't) get another out of the water, a safety line keeping the person near the vessel until assistance arrives is something to consider. Some have a strong enough D-ring (and vest design) to allow the use of the D-ring with a lifting strap. Fewer designs have a tag line that floats free to make it easier to catch that line with the boat hook if the person is incapacitated or having difficulty getting close to the vessel.
The little "Alka-Seltzer" tablets are effected by humidity. They may last several years on your boat, but when they pop off you will need to replace the Co2 cartridge, the indicator tab, and the tablet. It is much cheaper to routinely change out the tablet after examining it every season. Spare tablets aboard need to be in a sealed container like a little jar, preferably with a moisture absorber (the little sachet that says "Don't Eat This" that we usually throw away).
Another thing that you might consider is actually testing the vest. Not only to see if it works, but to acquaint yourself with its actual use. Watching a YouTube video goes only so far. For the waist belt versions, you need to thread your head through the horse collar. They tend to pop open in an alarming way. If it doesn't, you need to understand the manual inflate tube. All something that can be worth playing in the pool and spending $25 to rearm. Don't have your own pool? Every lifeguard I've ever spoken with about testing has been very receptive to using their pool to learn about PFDs. You will likely draw a crowd.