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This is why the discussion goes on and on.... apples and oranges unless you make a close comparison to nearly or the same boat....
Exactly!
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My main point is that for most every pro or con, some designer has designed some modification to overcome the con that may or may not lead to just another con....
As an example of the above, we are interested in a boat that can have a single or twins. The advantage of the twins vs a single engine, for our use is, and in order of importance,
1 - The boat can dry out while not listing.
2 - The smaller engine can be used as a generator when needed.
3 - Being able to run at slow speeds on one, properly loaded engine.
4 - Having a backup engine.
5 - Maneuverability
However, there is a design cost. A big one as far as I am concerned, is lack of engine room space. The engine room is a crawl in cave and there is not much space for a single engine and this is made worse with two engines. The engine room space/cave is a design choice to lower the air draft of the boat, which is very important for us.
The ER is very cramped. There are things that can be done to improve access, but it will always be tight with a single, and much more so with twins.
One of the advantages of the boat is that it has quite a bit of space for solar power. So much so, that for most of the year, even in high latitudes, the solar panel will handle most/all electrical needs. This really opens up the idea of using hybrid propulsion. Now, some hybrids run off the engine drivetrain, so having twins with hybrids really increases the cost, and in our case, makes the engine room space even more confined. This really says that this type of hybrid with twins is a no go.
However, there are other electrical propulsion options that are NOT attached to the diesel drivetrain which has it's advantages.
So, in our case and our usage, having a singe diesel with a separate hybrid propulsion system, along with a standalone generator, makes more sense than having twins. This maximizes the higher priority requirements but at the cost of being able to dry out the boat without it having a list.
Change the requirements and one would change the equipment and boat design choices, with the same exact hull. None of the choices are right or wrong, they just are.