Myrtle Beach area is much less expensive than the Charleston area...pretty much the same weather.
Just depends on what you like in a homeport.
Plenty to do in either...just different flavor. Better boating in Charleston..but for a multi-month layover...bet you can find slips half price north of Charleston to the N. Carolina Border...plus don't know about Charleston...but in Myrtle Beach area you are forgiven up to 180 days before you are subject to taxes...possible registration too. Can't say for Charleston area.
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