I lived on a Uniflite 42 ACMY (aft cabin motoryacht - same layout as a Sundeck trawler). I'd say the biggest drawbacks are simply getting on and off the boat. Bringing groceries aboard. On/off dinghy. And of course docking - can be a bit challenging to get a mate on the dock.
Not sure where you're located, but if your area have fixed fingers, might be easier as they tend to be pretty high compared to floating docks.
I'll add that as nice as the aft deck is, it always felt a bit detached from the water. I've been a sedan guy ever since.
Lot of benefits. You just have to decide if the tradeoff makes sense. Lot of nice interior living space in a Sundeck.
1970 Willard 36 Sedan Trawler