Commas are good!
Sometime not using them can result in your inadvertently being branded a misogynist of the worst type, or even end in a gruesome death of a loved one, not to mention making your posts unintelligible.
"WOMEN WITHOUT HER MAN IS WORTHLESS" (welcome to OTDE)
"WOMEN, WITHOUT HER, MAN IS WORTHLESS"( SNAG)
" LET'S EAT GRANDMA" (Hannibal Lecter, aged six)
" LET'S EAT, GRANDMA" ( Hannibal Lecter's vegetarian brother)