I have a '78 Mainship 34, and have put 8000 miles on it in 3 years, almost all single-handed. Twice through the Rideau, Trent Severn, and western Erie canals as well as down the Mississippi from the great lakes to Florida. It's the first inboard power boat I've owned, so I can't speak to features or handling vs alternative boats. But the boat has served me well. Lots of room for one or two and good economy at slow speeds. I have lots of experience with single handing sailboats up to about 40 feet and haven't had any problems maneuvering with the boat.
I might have been equally happy in a smaller boat like a Cape Dory 28, but don't regret my choice of boat. If you can find one in good shape it's a fine choice.
I almost always drive from the flybridge, so the lack of a side door hasn't bothered me. Have gotten pretty good at scampering up and down the ladder