Master in the bow gets the best airflow at anchor. And with this hull, no annoying chine slap like in my old Mainship. Its a trade off for 2 staterooms with a single level cockpit/salon/swim platform (not raised or flush deck) fit into a 42' boat. I didn't want an aft cabin.
As for climb over bed, we are younger than some, so not a bother. We did modify the center drawer into a pullout step. Makes things alot easier. For us the second stateroom is a pantry/storage room that someone may sleep in occasionally.
To OP, I am 6'0" and sleep next to the wall using the angle for more matress length. On occasion it feels tight. Any taller and I wouldn't be happy.