The only real difference in my experience would be availability when crowded. Logic says that the larger the boat you own, the less different size spaces you will fit in. If a marina has sizes from 40 to 70' in ten foot increments, with more sizes for the smallest slips and fewest sizes for the largest slips, a 60' boat will only fit in 60 and 70' slips, whereas a 40' boat will fit in all. So, you are competing for a much smaller percentage of the slips. When the marina gets near full, bigger slips get filled with smaller boats. My experience with a 50' overall length boat during Snowbird migration is that you need to be able to book several days in advance to guarantee availability.
I would guess most marinas have spaces for a 60' boat. You might consider going on Dockwa or one of the other marina booking sites, and see what's available in maybe 10 areas along your proposed route.
Ted