An update to all of you that responded to my original post: We did the trip early March under a full moon. The route was departing Palmetto FL at 11:00am, exit Tampa bay south of Egmont, then direct to Dry Tortugas arriving roughly 11:00am the next day after a non stop run. The only pots we saw were within the first few hours. By late afternoon we were out far enough and/or in deep enough water for their to be virtually no pots. We did pass one other boat (a sailboat also heading south) and also came within 1/2 mile of another boat running without lights in a light fog at 3:00am. As we approached the Tortugas in daylight we did dodge a few larger shrimp boats at anchor, crew nowhere to be seen. It was a great run, for anyone considering the same. Thanks for the comments and suggestions. (The boat was a 48' Kadey Krogen, 8 knot cruise, 5' draft).