For a small motor vessel, (up to 55'), only the inside passage is recommendable.
Even so, weather forecasts are always far from being accurate.
The months between December and March are the best ones to make this inside passage.
Thank capacity is a must.
I don't know any positive feedback from those who tried to go from East to West. Specially in the inside passage. East coast of southern Argentina is not a gentle territory and there ain't many places where you can hide.
I have done this passage twice. In a 65' sailboat from Punta Arenas to Comodoro Rivadavia, as part of a crew that went to pick up a racing boat bought in Hawai. I was 20 y.o. and I remember having regret the money. The name of the boat was SAGA.
The second time was 14 years ago in a cruise ship with my wife. Trip not repeatable, because you cannot eat soup from your shoes