There are of course some construction techniques with advantages over others. For example with cored fiberglass a honeycomb core is, to me anyway, superior than a wood core. Unlike wood, it won't rot and if water gets in it will not spread past where the leak is. There are hundreds if not thousands of choices like these in designs and materials. However unless you're custom building from scratch many have been made for you. And if you're buying used, well most all have. What i think it's better to focus on is what do you want to do with the boat in the next 5-6 years.
This will formulate a list of needs. You can split them into "must haves" and "like to have" then back into the design, materials and construction of the boats that fit the bill.
For example, if I were buying a boat to do the great loop a must have is a max height under a certain amount so I can fit under all bridges. On the other hand stabilizers may be a nice to have if needed at all. However if I was buying a boat to cruise back and forth from Bermuda, I wouldn't care about the max height but stabilizers become a must have.
I think with your list of needs then looking at what's available in your budget becomes an easier approach.